Copper-binding signal peptide
Copper Peptide (GHK-Cu)
INCI: Copper Tripeptide-1·Studied at 1–2%·Moderate evidence
A naturally occurring copper-binding tripeptide widely used in topical formulas and studied for its role in the appearance of skin firmness and texture.
Studied for
- ·The appearance of firmness and elasticity
- ·The look of skin smoothness and texture
- ·Supporting the skin’s visible renewal
How it’s thought to work
Studied as a signal peptide that delivers copper and is associated with matrix-remodeling activity in skin-model research.
Layering note
Often kept apart from: direct L-ascorbic acid (vitamin C).
Questions
- Can I use copper peptides with vitamin C?
- They are commonly separated to different routines (for example one in the morning, one in the evening). Layered directly, strong L-ascorbic acid can affect the copper complex, so most guides suggest not applying them at the same time.